陈赫出生于医学世家，是医术精湛的外科医生，手术成功率高达100%，其女友也同为一名医生。陈赫由于意外穿越回150年前的李氏朝鲜，遇到了日后的政治名人兴宣大院君、最高武士金景卓及同现代女友面容几乎一模一样的洪英莱……精湛的医术改变着古人的命运，使自己卷入了历史的波涛，而陈赫也在其中认识了自己的人生……
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